{"product_id":"9781803568065","title":"Brca1 And Brca2 Mutations - Diagnostic And Therapeutic Implications","description":"Mutations in the BRCA1\/2 genes are the most common cause of hereditary breast and ovarian cancer (HBOC), and HBOC is an autosomal dominant cancer predisposition syndrome. Individuals with HBOC have a high risk for breast and ovarian cancers and a moderate risk for other cancers, such as prostate, pancreatic, melanoma, and fallopian tube cancers. The goal of screening individuals at high risk of familial cancer is either prevention (such as a change in lifestyle or diet) or early detection of cancer. The identification of BRCA mutation carriers is important, since increased surveillance, drug therapy, and prophylactic surgery can reduce cancer-related morbidity and mortality. In recent years, there has been substantial development in BRCA-associated hereditary breast and\/or breast-ovarian cancer research and its clinical applications. In this context, this book consolidates the recent advances in BRCA-related cancer biology and therapeutics, covering a wide spectrum of interrelated topics. Chapters cover a wide range of topics, such as BRCA discovery, BRCA structure and function, BRCA-associated cancers, BRCA genetic testing and counselling, and more. This book is a valuable resource not only for medical and allied health students but also for researchers, clinical and nurse geneticists, genetic counselors, and physician assistants.\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cul\u003e\n\u003cli\u003e| \u003cb\u003eAuthor: \u003c\/b\u003eMani T. Valarmathi\u003c\/li\u003e\n\u003cli\u003e| \u003cb\u003ePublisher: \u003c\/b\u003eIntechopen\u003c\/li\u003e\n\u003cli\u003e| \u003cb\u003ePublication Date: \u003c\/b\u003eJan 18, 2023\u003c\/li\u003e\n\u003cli\u003e| \u003cb\u003eNumber of Pages: \u003c\/b\u003e134 pages\u003c\/li\u003e\n\u003cli\u003e| \u003cb\u003eLanguage: \u003c\/b\u003eEnglish\u003c\/li\u003e\n\u003cli\u003e| \u003cb\u003eBinding: \u003c\/b\u003eHardcover\u003c\/li\u003e\n\u003cli\u003e| \u003cb\u003eISBN-10: \u003c\/b\u003e1803568062\u003c\/li\u003e\n\u003cli\u003e| \u003cb\u003eISBN-13: \u003c\/b\u003e9781803568065\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Intechopen","offers":[{"title":"Default Title","offer_id":48050710872369,"sku":"9781803568065","price":122.4,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0798\/8215\/8385\/products\/9781803568065.jpg?v=1704635692","url":"https:\/\/www.recomparo.com\/products\/9781803568065","provider":"ReComparo.com","version":"1.0","type":"link"}